Description
Sulindac (Clinoril) is a non-steroidal anti-inflammatory agent of the arylalkanoic acid class.Treatment of human colorectal cancer cell lines induces MRP1 and MRP3 but not other members of the MRP family. Reported to significantly increase the cytotoxicity of the anthracyclines (doxorubicin, daunorubicin and epirubicin), as well as teniposide, VP-